In the paper,a multi-channel multi-sample rate data uniform collection and editing system is designed based on FPGA for the accuracy requirements of signal acquisition of the acquisition system.The system is based on the Spartan-6 series FPGA as the main controller.The hardware part:the third-order active low-pass filtering is used to anti-alias the signal to ensure the accuracy of data acquisition.The logic design part:reading the ROM address table sends the signals of different sample rates to the true 12-bit analog-to-digital conversion chip at a switching frequency of 1 137 ns through the analog switch to achieve efficient acquisition timing.After physical testing,for different gear analog signals can achieve high-precision acquisition with a acquisition accuracy of better than 0.5%,which fully meets the design requirements and has been applied to actual production.