System exception handling is essential in the multi-core heterogeneous SoC application of KeystoneII architecture,and the ability to handle exception problems is also an important standard to measure system stability.Based on the C66x core of the high-performance SoC TMS320C66AK2H,this paper uses the C66x core interrupt controller and the chip interrupt processing controller to implement a system exception handling method,which can accurately and quickly locate the place where the system runs incorrectly.Finally,the DSP core 0 uses the EDMA3 module to illegally access the shared memory MSMC as an example to verify the feasibility of the system exception handling method.The test results show that the exception handling method is accurate and effective.