In the paper,FR8016 microcontroller and MAX30102 sensor are mainly used to realize the data collection,calculation and storage of human wrist or finger heart rate and blood oxygen concentration.MAX30205 sensor is used to collect human body temperature and transmitted to the mobile phone APP for display and data storage through Bluetooth encryption of the microcontroller.When the device is disconnected from the mobile phone,data is stored in the local Flash of the microcontroller and uploaded after the connection is successful.It has low power consumption and high reliability,and it is applicable to daily life.